In 1517 Sir Thomas More was the Master of Requests an office  he held from 1514, he was also a member His Majesty’s Most Honourable  Privy Council.
1517  saw the third outbreak of Sweating Sickness’ which was a more severe  epidemic. In the midst of this terrible outbreak Thomas More conveys his  concerns. –  
“We  are in grief and danger as never before. Many are dying all round us,  and almost everybody at Oxford, Cambridge and London has been laid up  within the last few days. Many of our best and most honorable friends  have perished: among these – I grieve for the grief it will give you –  Andrew Ammonio, in whom good letters and all good men have suffered a  great loss. He thought himself protected against contagion by his  temperance in food. It was due to this, he thought, that his whole  household escaped, whilst almost everybody he met had their families  laid up. He boasted to me and to many others of this, a few hours before  he died. For in the Sweating Sickness death always comes, if it does  come, on the first day. I, with my wife and children, am as yet  untouched: the rest of my household has recovered. I tell you, there is  less danger on a battle front than in London. And now, i hear, it is  beginning to rage in Calais just as we are being driven there on  diplomatic business – as if it were not enough to have lived among  infection, but one must follow it when it goes.”
A description of Sweating Sickness can be found in the Encyclopedia Britannica, published in 1911:
SWEATING-SICKNESS. 
A  remarkable form of disease, not known in England before, attracted  attention at the very beginning of the reign of Henry VII. It was known  indeed a few days after the landing of Henry at Milford Haven on the 7th  of August 1485, as there is clear evidence of its being spoken of  before the battle of Bosworth on the 22nd of August. Soon after the  arrival of Henry in London on the 28th of August it broke out in the  capital, and caused great mortality. This alarming malady soon became  known as the sweating-sickness. It was regarded as being quite distinct  from the plague, the pestilential fever or other epidemics previously  known, not only by the special symptom which gave it its name, but also  by its extremely rapid and fatal course. 
From  1485 nothing more was heard of it till 1507, when the second outbreak  occurred, which was much less fatal than the first. In 1517 was a third  and much more severe epidemic. In Oxford and Cambridge it was very  fatal, as well as in other towns, where in some cases half the  population are said to have perished. There is evidence of the disease  having spread to Calais and Antwerp, but with these exceptions it was  confined to England. 
In  1528 the disease recurred for the fourth time, and with great severity.  It first showed itself in London at the end of May, and speedily spread  over the whole of England, though not into Scotland or Ireland. In  London the mortality was very great; the court was broken up, and Henry  VIII. left London, frequently changing his residence. The most  remarkable fact about this epidemic is that it spread over the  Continent, suddenly appearing at Hamburg, and spreading so rapidly that  in a few weeks more than a thousand persons died. Thus was the terrible  sweating-sickness started on a destructive course, during which it  caused fearful mortality throughout eastern Europe. France, Italy and  the southern countries were spared. It spread much in the same way as  cholera, passing, in one direction, from north to south, arriving at  Switzerland in December, in another northwards to Denmark, Sweden and  Norway, also eastwards to Lithuania, Poland and Russia, and westwards to  Flanders and Holland, unless indeed the epidemic, which declared itself  simultaneously at Antwerp and Amsterdam on the morning of the 27th of  September, came from England direct. In each place which it affected it  prevailed for a short time only – generally not more than a fortnight.  By the end of the year it had entirely disappeared, except in eastern  Switzerland, where it lingered into the next year;’ and the terrible  “English sweat” has never appeared again, at least in the same form, on  the Continent. 
England  was, however, destined to suffer from one more outbreak of the disease,  which occurred in 1551, and with regard to this we have the great  advantage of an account by an eyewitness, John Kaye or Caius. the  eminent physician. 
Symptoms
The  symptoms as described by Caius and others were as follows. The disease  began very suddenly with a sense of apprehension, followed by cold  shivers (sometimes very violent), giddiness, headache and severe pains  in the neck, shoulders and limbs, with great prostration. After the cold  stage, which might last from half-an-hour to three hours, followed the  stage of heat and sweating. The characteristic sweat broke out suddenly,  and, as it seemed to those accustomed to the disease, without any  obvious cause. With the sweat, or after that was poured out, came a  sense of heat, and with this headache and delirium, rapid pulse and  intense thirst. Palpitation and pain in the heart were frequent  symptoms. No eruption of any kind on the skin was generally observed;  Caius makes no allusion to such a symptom. In the later stages there was  either general prostration and collapse, or an irresistible tendency to  sleep, which was thought to be fatal if the patient were permitted to  give way to it. The malady was ‘ Guggenbiihl, Der englische Schweiss in  der Schweiz (Lichtensteig, 1838). 
Remarkably  rapid in its course, being sometimes fatal even in two or three hours,  and some patients died in less than that time. More commonly it was  protracted to a period of twelve to twenty-four hours, beyond which it  rarely lasted. Those who survived for twenty-four hours were considered  safe. 
The disease,  unlike the plague, was not especially fatal to the poor, but rather, as  Caius affirms, attacked the richer sort and those who were free livers  according to the custom of England in those days. “They which had this  sweat sore with peril of death were either men of wealth, ease or  welfare, or of the poorer sort, such as were idle persons, good ale  drinkers and taverne haunters.” Causes. – Some attributed the disease to  the English climate, its moisture and its fogs, or to the intemperate  habits of the English people, and to the frightful want of cleanliness  in their houses and surroundings which is noticed by Erasmus in a  well-known passage, and about which Caius is equally explicit. But we  must conclude that climate, season, and manner of life were not  adequate, either separately or collectively, to produce the disease,  though each may have acted sometimes as a predisposing cause. The  sweating sickness was in fact, to use modern language, a specific  infective disease, in the same sense as plague, typhus, scarlatina or  malaria. 
The only  disease of modern times which bears any resemblance to the  sweating-sickness is that known as miliary fever (“` Schweiss friesel,”  “suette miliaire” or the “Picardy sweat”), a malady which has been  repeatedly observed in France, Italy and southern Germany, but not in  the United Kingdom. It is characterized by intense sweating, and occurs  in limited epidemics, not lasting in each place more than a week or two  (at least in an intense form). On the other hand, the attack lasts  longer than the sweating-sickness did, is always accompanied by eruption  of vesicles, and is not usually fatal. The first clearly described  epidemic was in 1718 (though probably it existed before), and the last  in 1861. Between these dates some one hundred and seventy-five epidemics  have been counted in France alone.
                                                     
                     